A Bit About Neurotoxins
The most popular neurotoxin, Botox, is a neurotoxic protein injection that paralyzes chemical signals that cause muscles to contract. Botox is the brand most are familiar with, but there are also many other types of neurotoxins such as Jeuveau, Dysport, and Xeomin.
The most common use of these injections is to temporarily relax the facial muscles that cause wrinkles in the forehead and around the eyes. So, Botox injections are most often used for softening the lines on the forehead, the area where microblading or other permanent eyebrow treatments are done.

Neurotoxin Before PMU: Is It Safe?
Yes, getting neurotoxin before PMU (e.g. microblading, powder brows, nano brows etc.) is perfectly safe, but only if it’s done at least 15 days prior to the initial PMU treatment and then again 15 days prior to retouch appointment.
Why Does Botox Have to Be Done 15 Days Before PMU Brow Procedure?
Neurotoxin needs some time to settle and take effect. The risk is that Botox may move from the area where it has been injected and can cause facial paralyzation if it isn’t settled yet (we don’t want that!).
Therefore, it’s important to wait at least 2 weeks between neurotoxins and microblading to make sure it has completely settled and it’s safe to treat the brow area. If possible wait a bit longer, just to be sure.
How Long After PMU Brow Procedure Do I Have to Wait to Do Botox?
You can have neurotoxins done immediately after your flowy brow, microblading or other brow PMU appointment. Neurotoxins are injected into the muscle, so they won’t affect your results or healing of the pigment, and they can be done immediately after if you wish.
So, Which Should I Do First: Neurotoxin or Microblading?
Nano Stroking, Microblading, Powder Brow, or other brow PMU treatments are typically recommended before neurotoxin. Micropigmentation lasts 1-2 years and neurotoxin lasts 3-6 months.
It is best to do your eyebrows first because the design is based on your natural bone structure. Neurotoxins may alter the appearance of your muscles for a short amount of time and should you decide to cease Botox treatments, your brows will settle at their original balanced position.

Playing Devil’s Advocate: the Pro of Neurotoxin Before PMU
Even though it’s generally recommended to get neurotoxins after PMU, as an artist I am more of a fan of getting neurotoxin injections before PMU.